Stress and pluripotency

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Stress and pluripotency

Vacanti and colleagues recently reported the generation of mouse cells exhibiting pluri/totipotency by stress treatment, and showed that these cells can give rise to chimeras and clonal adults (Obokata et al., 2014a,b). The findings were controversial, and the authors have now retracted the papers, citing multiple critical errors within the reports that impaired the credibility of the findings ...

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Pluripotency and nuclear reprogramming.

Embryonic stem cells are promising donor cell sources for cell transplantation therapy, which may in the future be used to treat various diseases and injuries. However, as is the case for organ transplantation, immune rejection after transplantation is a potential problem with this type of therapy. Moreover, the use of human embryos presents serious ethical difficulties. These issues may be ove...

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Totipotency/pluripotency and patentability.

UNLABELLED In their article entitled " COMMENTARY Is totipotency of a human cell a sufficient reason to exclude its patentability under the European law" (Stem Cells 2007;25:3026-3028), K.T. Vrtovec and B. Vrtovec conclude that arguments based on differentiation potential should not be an obstacle to patenting human embryonic stem cells (and related cells referred to as totipotent or pluripot...

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ژورنال

عنوان ژورنال: Frontiers in Cell and Developmental Biology

سال: 2014

ISSN: 2296-634X

DOI: 10.3389/fcell.2014.00032